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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM83F
All Species:
16.97
Human Site:
S61
Identified Species:
41.48
UniProt:
Q8NEG4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEG4
NP_612444.2
500
55486
S61
Q
L
R
D
F
L
S
S
P
E
R
Q
A
L
R
Chimpanzee
Pan troglodytes
XP_001151451
585
64152
S61
Q
L
R
D
F
L
S
S
P
E
R
Q
A
L
R
Rhesus Macaque
Macaca mulatta
XP_001100816
501
55543
S61
Q
L
R
D
F
L
S
S
P
E
R
Q
A
L
R
Dog
Lupus familis
XP_531728
581
63261
Q135
L
R
G
F
L
S
S
Q
E
Q
Q
A
L
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3UKU4
495
54994
S61
R
L
R
D
F
L
S
S
Q
E
R
Q
A
L
C
Rat
Rattus norvegicus
NP_001123974
500
55607
D57
V
K
K
E
R
L
R
D
F
L
S
S
Q
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520189
566
61788
P61
M
A
R
E
G
M
V
P
F
L
G
A
E
E
A
Chicken
Gallus gallus
XP_001234070
507
57553
S61
R
L
Q
D
F
L
S
S
Q
E
L
Q
A
L
R
Frog
Xenopus laevis
Q5XK72
933
103894
D57
V
K
G
E
N
I
R
D
F
L
S
E
L
E
M
Zebra Danio
Brachydanio rerio
A4QP72
534
59983
E62
R
M
P
N
F
L
S
E
D
E
I
R
R
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.9
96.4
70.4
N.A.
80.5
80.5
N.A.
28.2
57
26.5
28.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
81.3
98.1
76.4
N.A.
87.5
87.8
N.A.
43.4
72.1
36.7
45.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
80
13.3
N.A.
6.6
73.3
0
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
86.6
26.6
N.A.
20
86.6
20
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
20
50
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
50
0
0
0
20
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
30
0
0
0
10
10
60
0
10
10
30
0
% E
% Phe:
0
0
0
10
60
0
0
0
30
0
0
0
0
0
0
% F
% Gly:
0
0
20
0
10
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
20
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
50
0
0
10
70
0
0
0
30
10
0
20
50
0
% L
% Met:
10
10
0
0
0
10
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
10
30
0
0
0
0
0
0
% P
% Gln:
30
0
10
0
0
0
0
10
20
10
10
50
10
0
0
% Q
% Arg:
30
10
50
0
10
0
20
0
0
0
40
10
10
10
50
% R
% Ser:
0
0
0
0
0
10
70
50
0
0
20
10
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
20
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _